Meridian Star

New Today

January 2, 2013

Hunger games: The new science of fasting

(Continued)

Various hormones are also affected. For example, production of insulin-like growth factor 1 (IGF-1) drops early and reaches very low levels by Day 3 or 4. It is similar in structure to insulin, which also becomes scarcer with fasting, and high levels of both have been linked to cancer.

As for treating cancer, Valter Longo, director of the Longevity Institute at the University of Southern California, thinks that short-term complete fasts maximize the benefits. He has found that a 48-hour total fast slowed the growth of five of eight types of cancer in mice, the effect tending to be more pronounced the more fasts the animals undertook.

Fasting is harder on cancer cells than on normal cells, he says. That's because the mutations that cause cancer lead to rapid growth under the physiological conditions in which they arose, but they can be at a disadvantage when conditions changes. This could also explain why fasting combined with conventional cancer treatment provides a double whammy. Mice with gliomas — very aggressive forms of cancer and the most commonly diagnosed brain tumor in people — were more than twice as likely to survive a 28-day study if they underwent a 48-hour fast accompanied by radiation therapy as were those that did not fast.

Could fasting prevent cancers from developing in the first place? Evidence is scant.

Longo says there are "very good reasons" why it should. He points out that high levels of IGF-1 and glucose in the blood and being overweight are risk factors for cancer, and they can all be improved by fasting.

Another risk factor is insulin, says Michelle Harvie at Britain's University of Manchester. Studying a group of women whose family history put them at high risk of developing breast cancer, she put half of them on a diet that cut calories by about 25 percent and half on a 5:2 fast. After six months, both groups showed a reduction in blood insulin levels, but the reduction was greater in the fasting group. Harvie's team is now analyzing breast biopsies to see whether this translates to fewer of the genetic changes associated with increased cancer risk.

Text Only
New Today
Biz Marquee
New Today
Poll

A majority of House members approved a motion to sue President Obama for exceeding his constitutional boundaries. The lawsuit will focus on the presidents overhaul of health care. Do you think the lawsuit is warranted?

Yes
No
     View Results
Facebook
Facebook
Twitter Updates
Follow us on twitter
AP Video
Renewed Violence Taking Toll on Gaza Residents 2 Americans Detained in North Korea Seek Help US Employers Add 209K Jobs, Rate 6.2 Pct House GOP Optimistic About New Border Bill Gaza Truce Unravels; Israel, Hamas Trade Blame Raw: Tunisia Closes Borders With Libya Four Rescued From Crashed Plane Couple Channel Grief Into Soldiers' Retreat WWI Aviation Still Alive at Aerodrome in NY Raw: Rescuers at Taiwan Explosion Scene Raw: Woman Who Faced Death Over Faith in N.H. Clinton Before 9-11: Could Have Killed Bin Laden Netanyahu Vows to Destroy Hamas Tunnels Obama Slams Republicans Over Lawsuit House Leaders Trade Blame for Inaction
Hyperlocal Search
Premier Guide
Find a business

Walking Fingers
Maps, Menus, Store hours, Coupons, and more...
Premier Guide